Group Leader : Daniela Piancatelli

Istituto

Istituto di Farmacologia Traslazionale,
Via Carducci 32,  6710 –  L’ Aquila
http://www.ift.cnr.it/

Membri del Laboratorio

Anna Aureli anna.aureli@cnr.it

Angelica Canossi angelica.canossi@cnr.it

Daniela Piancatelli daniela.piancatelli@cnr.it

Attività

HLA polymorphism in transplantation and diseases. Polymorphisms of non classical HLA and HLA-related loci. Tolerance and immune disregulation in kidney transplantation. Role of Fc γ receptor and KIR/HLA in cancer and degenerative diseases. Cytokines in diseases. Immunogenetics of Alzheimer disease and developmental neurological disorders. Characterization of novel alleles. Population genetics; immunogenetics of celiac disease.

 

CIN website:

  1. Piancatelli – Classical and non-classical HLA, immunogenetics of transplantation and diseases (celiac, Alzheimer disease); population genetics.
    A. Aureli – Fc receptors, CD1 and BDNF in cancer and diseases.
    A. Canossi – Immunogenetics of Treg biomarkers in organ transplantation (CTLA4, FOXP3); KIR/HLA in cancer and immune-related diseases.

Principali progetti e collaborazioni

DSB.AD007.043 “Marcatori biomolecolari e genetici in patologie immunologiche e neurodegenerative”.

Strumenti / Tecnologie

Sequence-based typing, genotyping/allelic discrimination, gene expression (RT-PCR), cell cultures, ELISA.

Group Leader
Silvia Di Loreto

Istituto

Istituto di Farmacologia Traslazionale – UOS L’ Aquila
VIA CARDUCCI 32 0862.318843
67100 – L’AQUILA
Tel: 086.2318843
http://www.ift.cnr.it

Membri del Laboratorio

Anna Aureli (ric III°) anna.aureli@cnr.it

Annamaria Berghella (ric III°) annamaria.berghella@cnr.it

Angelica Canossi (ric III°) angelica.canossi@cnr.it

Patrizia Pellegrini (Tecnol II°) patrizia.pellegrini@cnr.it

Daniela Piancatelli (ric III°) daniela.piancatelli@cnr.it 

Attività

HLA polymorphism in diseases and transplantation. Polymorphisms of non classical HLA loci (MICA, HLA-G) and HLA-related loci. Role of Fc γ, CTLA-4, PD-1 and KIR Receptors in cancer and degenerative diseases. Cytokines and cytokine gene polymorphisms in immune-related and degenerative diseases. Immunogenetics of Alzheimer disease and developmental neurological disorders. Characterization of novel alleles. Population genetics. Immunogenetics of celiac and atopic diseases.

Strumenti / Tecnologie

  • Sequence-based typing
  • genotyping/allelic discrimination techniques
  • cell cultures
  • ELISA